Atomic and Molecular Biospectroscopy Group

Description
The scientific activity of the Atomic and Molecular Biospectroscopy Group is focused on the applications of the advanced spectroscopic methods in investigation of elemental (XRF microscopy, TXRF spectroscopy) and biochemical changes (FTIR, Raman microspectroscopy, SERS, TERS) occurring in cells, tissues and organs, as a result of physiological and pathological processes of different ethology. The conducted research concerns, among others, identification of: (1) neuroprotective mechanisms and potential side effects of ketogenic diet, (2) biomolecular markers of glioblastoma multiforme development in brain, (3) potential toxicities of the iron oxide magnetic nanoparticles (commercially available and dedicated) under in vivo and in vitro conditions and (4) methodological development of spectroscopic and microscopic studies of intact red blood cells (RBCs) and vascular endothelial cells (ECs) enabling the analysis of single cells and interactions between RBCs and ECs in in vitro and ex vivo conditions. Moreover, the investigation of the Group is focused on the evaluation of the usefulness and implementation of instrumental methods based on atomic and molecular spectroscopy for the analysis of microplastics and nanoparticles in the environmental and biomedical samples. Mossbauer studies enable tracking the fate of iron in biological samples, determining its concentrations and chemical forms in various detected phases. In synthetic samples, high entropy systems (alloys, oxides, sulphides), intermetallic phases and others are studied. The determined magnetic properties and hyperfine parameters are additionally analyzed based on the results of calculations of the electronic structure of these materials.
Research facilities:
Konfokalny mikroskop Ramana
Laboratories:
Laboratory of Atomic and Molecular Biospectroscopy
Mossbauer Spectroscopy Laboratory
Cooperation:
Łukasiewicz Research Network - PORT, Polish Center for Technology Development
National Synchrotron Radiation Center SOLARIS, Jagiellonian University
Laboratory for Applications of Synchrotron Radiation, Karlsruhe Institute of Technology
Department of Chemistry, University of Girona
Interdepartmental Research Service (SIdI), Autonomous University of Madrid
Center for Experimental and Innovative Medicine, University of Agriculture in Krakow
Institute of Zoology and Biomedical Research, Jagiellonian University
Institute of Physics, Jan Kochanowski University in Kielce
Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University
Faculty of Chemistry, Jagiellonian University
Małopolska Center of Biotechnology, Jagiellonian University
Institut für Festköperphysik, Technische Universität Wien
Groupe de Physique des Materiaux, Université Rouen Normandie

Contact

Joanna Chwiej
ul. Władysława Reymonta 21B, pok. 219
12 617 30 02

Leading unit

Faculty of Physics and Applied Computer Science - Department of Medical Physics and Biophysics

Team leader

Chwiej Joanna

Team members

  • Marzec Katarzyna M.
  • Bułat Katarzyna
  • Dróżdż Agnieszka
  • Matusiak Katarzyna
  • Saługa Marta
  • Wilkosz Natalia
  • Gol Jolanta
  • Kawoń Kamil
  • Rugieł Marzena
  • Wilk Aleksandra
  • Cieślak Jakub
  • Szymczak Maria
  • Sławek Anna

IDUB research areas

  • Water-energy-climate: interdisciplinary approach to sustainable development
  • Technical solutions: from fundamental research, through modelling and design, to prototypes. The application of mathematical, information technology, and electronics tools to macro-, micro-, and nanoscale problems
  • Design, production, and testing of modern materials and the technologies of the future based on a multidisciplinary approach combining materials engineering with chemistry, physics, mathematics, and medicine
  • Crossing boundaries: experimental high energy physics, extreme states of matter, advanced radiation detection technologies, transdisciplinary research and applications

Keywords

microplasticscell and tissue imagingnanotoxicitybiomolecular basis of physio- and pathological processesrentgenowska mikroskopia fluorescencyjnainfrared and Raman spectroscopy and imagingMossbauer spectroscopyelectronic structure calculations